Mycobacterium tuberculosis (M.tb) facts
- M.tb is the leading infectious cause of death worldwide.
- Globally, someone dies of tuberculosis (TB) every 17 seconds.
- There is currently no vaccine which will stop the epidemic.
Pictured from left to right: Chetan Seshadri, Quang Thong, Tori Tappen, Cassie Winter, Megan Files, Prerana Shrestha, Debbie Cross, Angela Zhou, Marysia Radka, Brooke Kennedy, Krystle Yu. Not pictured: Alicia Soman, Jordan McCrary
Photo Credit: Sadie Reitz. October 2025
Photo Credit: Sadie Reitz. October 2025
Our Mission
- Advance knowledge of immune factors required for protection against M. tuberculosis in humans
- Elucidate the functions and phenotypes of M.tb-specific T cell populations (classical and non-classical) using immunologic and computational approaches in collaborative human cohort studies
- Collaborate on other immune cell subsets or animal models if such studies extend the results of human studies
Our Recent Publications
- Probing dermal immunity to mycobacteria through a controlled human infection model.
- Specific CD4+ T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis.
- MR1-restricted T cell clonotypes are associated with "resistance" to Mycobacterium tuberculosis infection.
Quick Links
School of Medicine
750 Republican Street
Seattle WA 98109
750 Republican Street
Seattle WA 98109
Disclaimer: This page is not affiliated and does not reflect the view of the University of Washington
