Mycobacterium tuberculosis (M.tb) facts
- M.tb is the leading infectious cause of death worldwide.
- Globally, someone dies of tuberculosis (TB) every 17 seconds.
- There is currently no vaccine which will stop the epidemic.
Pictured from left to right: Debbie Cross, Patzy Villagrana, Megan Maerz, Elizabeth Ramirez, Megan Files, Stephen Makatsa, Nathan Kieswetter, Jolie Phan, Chetan Seshadri, Cassie Winter, Erik Layton, Krystle Yu, Emma Bishop, Tori Tappen, Angela Zhou
Our Mission
- Advance knowledge of immune factors required for protection against M. tuberculosis in humans
- Elucidate the functions and phenotypes of M.tb-specific T cell populations (classical and non-classical) using immunologic and computational approaches in collaborative human cohort studies
- Collaborate on other immune cell subsets or animal models if such studies extend the results of human studies
Our Recent Publications
- T-SPOT.TB reactivity in Southern African children with and without in utero HIV exposure.
- Cytotoxic T Cells Targeting Spike Glycoprotein Are Associated with Hybrid Immunity to SARS-CoV-2.
- Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells.